Words similar to cyclins
Example sentences for: cyclins
How can you use “cyclins” in a sentence? Here are some example sentences to help you improve your vocabulary:
Inhibition of cell cycle by p27 and p21 is complemented by retinoblastoma protein pRb, and other cell cycle inhibitors (tumor suppressor proteins) [ 30 31 32 ] . In reality, besides their role in the regulation of the cell cycle, the cdk inhibitors, in association with D-type cyclins, cyclin E, and cdk2, play a direct role in the stimulation of epithelial cell differentiation [ 33 ] . p27 is also transiently expressed in developing myotomes and enhances myogenesis [ 34 ] .
A characteristic phenotype of tumorigenic cells is their ability to grow anchorage-independently in suspension culture, or embedded in soft agar, without the need for attachment to the surface of a cell culture dish [ 25 26 ] . A flurry of papers has established a close link between anchorage-independent growth and the activity of several components of the cell cycle machinery, such as various cyclins, cyclin-dependent kinases (CDKs), and the CDK inhibitors p21 Cip1and p27 Kip1 [ 27 28 29 30 31 32 ] . There are indications that PTEN may be involved in these processes as well.
Current study supports our hypothesis that the immunosuppression results in an increased expression of cyclin inhibitor p21, which by inhibiting the expression of cyclins controls the allo-immune activation.
P-TEFb contains the cyclin-dependent kinase 9 (CDK9) and one of four possible C-type cyclins.
This suggests that the HIV-1-induced proliferation of infected renal epithelium may be caused by a cyclin D 1 -dependent mechanism, unlike other viruses that bypass a requirement for G 1 -phase cyclins to trigger aberrant cell-cycle progression.
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