Example sentences for: cyclopamine

How can you use “cyclopamine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Hh-blocking antibody 5E1 had no effect on pathway activation by the agonist (Figure 4b), while forskolin (Figure 4c), cyclopamine (Figure 4d) and Cur61414 (Figure 4e), were all inhibitory.

  • Specifically, the agonist appears somewhat resistant to the inhibitory effect of cyclopamine and Cur61414.

  • Related results demonstrating the action of cyclopamine on Smo have been reported by Beachy and colleagues [ 51 52 ] .

  • Identical results were seen using the slightly less active cyclopamine-related natural compound jervine, and the more potent synthetic derivative of cyclopamine, KAAD-cyclopamine (data not shown).

  • These results argue that the agonist activates the pathway downstream of the Hh-Ptc interaction while cyclopamine, Cur61414 and the agonist may act at a similar level in the Hh-signaling cascade.


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