Words similar to cyclopamine
Example sentences for: cyclopamine
How can you use “cyclopamine” in a sentence? Here are some example sentences to help you improve your vocabulary:
These results strongly support the model, initially hypothesized for cyclopamine [ 11 ] , that the reduced potency observed for Hh antagonists on Smo act-expressing cells is directly due to a reduced affinity of the antagonist for the mutated Smo protein.
Related results demonstrating the action of cyclopamine on Smo have been reported by Beachy and colleagues [ 51 52 ] .
It has been shown that the Hh-pathway antagonists cyclopamine and Cur61414 block signaling in a Ptc-independent manner [ 11 17 ] and therefore may act directly on Smo.
In contrast, the competition experiments with cyclopamine (Figure 4d) and Cur61414 (Figure 4e) showed that Hh protein and the agonist differ in their sensitivity to these antagonists.
Identical results were seen using the slightly less active cyclopamine-related natural compound jervine, and the more potent synthetic derivative of cyclopamine, KAAD-cyclopamine (data not shown).
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