Example sentences for: coregulated

How can you use “coregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As the membership cutoff decreases, additional genes will be assigned to each cluster group: in many cases, the similarity in the expression of the selected genes will exist over only a subset of the microarray experiments, promoting the identification of conditionally coregulated genes or genes whose products are more peripherally associated with the same cellular processes (see below).

  • The overlapping clusters identified by fuzzy k-means clustering also present more comprehensive groups of conditionally coregulated genes.

  • However, a key property of this algorithm (and many others like it) is that each gene is assigned to one and only one cluster, obscuring the relationships between conditionally coregulated genes such as those shown in Figure 1. This limitation is especially problematic when analyzing large gene-expression datasets that are collected over many experimental conditions, when many of the genes are likely to be similarly expressed with different groups in response to different subsets of the experiments.

  • Many of the genes that clustered together by fuzzy k-means clustering are likely to be coregulated at the level of transcription in response to certain environmental conditions.

  • The overlapping nature of the sets of coregulated genes supports the ability of the cell to customize the emergent genomic expression program to the particular needs of the cell, while minimizing the number of regulators required to produce each genomic expression program.


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