Words similar to coreceptor
Example sentences for: coreceptor
How can you use “coreceptor” in a sentence? Here are some example sentences to help you improve your vocabulary:
The individuals who controlled viremia for a longer time either during the first STI or during any of the treatment interruptions were not different from those who experienced earlier breakthrough as measured by ELISA and Western blot status at initiation of HAART, coreceptor polymorphisms (CCR5delta32, CCR2 V64I), or the presence or absence of GBV-C coinfection (Cox proportional hazards model, p >0.
The hypothesis that engagement of coreceptor binding sites on gp120 by CAP leads to the expression of gp41 six-helix bundle structures is supported by the finding that a tyrosine sulfated S-peptide, but not the non-sulfated peptide, from the N-terminus of CCR5 [ 25 56 57 ] has an effect similar to that of CAP (Fig.
Data reported so far suggest that the lethal hit to HIV-1 caused by CAP treatment involves the coreceptor binding site on gp120.
On the other hand, gp120-sCD4 complexes containing CAP treated gp120 bound to coreceptor expressing cells to a much lesser extent than similar complexes containing untreated gp120 (Fig.
The occupancy of CD4 and coreceptor binding sites by their respective ligands elicits downstream conformational changes in the envelope glycoprotein gp41, rendering it competent for fusion between virus and target cell membranes [ 18 19 40 41 42 43 ] . Shedding of gp120 from virus particles is not required for subsequent membrane fusion events [ 44 ] . The induction of gp41 six-helix bundles, detectable by mAb NC-1, by CAP in the absence of gp120 shedding is consistent with this conclusion.
Loading...