Example sentences for: coreceptor

How can you use “coreceptor” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Indeed, CAP binding to HIV-1 resulted in blockade of sites involved in coreceptor binding (Fig.

  • These more realistic choices of the route of infection and coreceptor usage will permit the assessment of the efficacy of the preventive intervention in a setting that more accurately reflects HIV exposures of humans, and will enable us to carefully investigate the processes that give rise to infection.

  • In agreement with this finding, CAP inhibited infection by both X4 and R5 viruses in in vitro models for vaginal HIV-1 infection [ 45 50 ] . Sites on the HIV-1 envelope other than the coreceptor binding domains may possibly be also involved in interactions with CAP, contributing to inhibition of virus infection.

  • In parallel to using more realistic, lower challenge doses, other crucial parameters of the experimental infection process, such as the route of transmission and the coreceptor usage of the challenge virus, should also be chosen to be as realistic as possible.

  • Engagement of the gp120 coreceptor binding site with a tyrosine sulfated peptide from the N-terminus of the coreceptor CCR5 [ 25 ] , shown to inhibit infection by CCR5-dependent, but not CXCR4-dependent, HIV-1 isolates, was sufficient to increase the expression of the gp41 six-helix bundles in HIV-1 BaL virus particles (Fig.


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