Words similar to coreceptors

Example sentences for: coreceptors

How can you use “coreceptors” in a sentence? Here are some example sentences to help you improve your vocabulary:

Pretreatment with CAP impairs gp120 binding to coreceptors
Thus, CAP would be expected to affect one or more steps required for HIV-1 entry into cells, i.e. binding to cellular CD4, to the major HIV-1 coreceptors CXCR4 or CCR5 for X4 and R5 viruses [ 6 ] , respectively, and fusion with cell membranes [ 7 8 9 10 11 12 13 14 15 ] . Results presented here show that CAP pretreated HIV-1 has a reduced capacity to bind to the coreceptors leading to impaired virus infectivity.
Thus, it would be expected that CAP would not inhibit the attachment of HIV-1 to target cells and would block only subsequent steps obligatory for HIV-1 infection initiated by engagement of CXCR4 and CCR5 coreceptors, respectively.
Data presented here show that CAP remains bound to HIV-1 after removal of unreacted compound, impairing virus infectivity due to blockade of binding sites for cellular coreceptors CXCR4 and CCR5.
These results indicate that treated HIV-1 particles, utilizing either CXCR4 or CCR5 as coreceptors, retain CAP on their surface and suggest that this is responsible for the altered properties and impaired infectivity of the treated viruses.