Words similar to corepressor

Example sentences for: corepressor

How can you use “corepressor” in a sentence? Here are some example sentences to help you improve your vocabulary:

Thus, corepressor complex HDACs must play an unspecified role in restricting the transcriptional activity of both ERβ and, in particular, the ERβ-LBD.
Consistent with this notion, the apparent weak transcriptional activity of the ERβ LBD is a consequence of corepressor HDAC activity at some level (Fig.
NRs generally interact with the corepressors N-CoR and SMRT either in the absence of ligand, or in the presence of receptor antagonists, and agonists promote corepressor release [ 4 ] . In this study, we demonstrated that ERβ binds to N-CoR in the presence of ER agonists such as estradiol and DES and the phytoestrogens genistein and coumestrol, but not in the presence of SERMs.
N-CoR Nuclear receptor corepressor
The nuclear receptor (NR) family comprises 48 structurally related transcription factors, many of which require their cognate ligand for activity [ 1 2 3 ] . The NRs regulate transcription by binding to response elements in the promoters of target genes and acting as scaffolds for the assembly of large coactivator and corepressor complexes [ 4 ] . NR coactivators include the p160s (including GRIP1/TIF-2, SRC-1 and AIB1/ACTR/pCIP).