Words similar to conformational
Example sentences for: conformational
How can you use “conformational” in a sentence? Here are some example sentences to help you improve your vocabulary:
Single strand conformational polymorphism (SSCP) analysis was performed on all coding exons using primers flanking intronic sequences of the MGMT gene by standard methods.
The conformational changes lead to the formation of a coiled-coil in gp41, consisting of three NH 2 -terminal leucine/isoleucine zipper regions, each contributed by one of the three subunits of the envelope glycoprotein trimer.
Human Fhit [ 14 ] and the S. cerevisiae Fhit homolog [ 13 ] , which was called Aph1 but is here termed Hnt2 under nomenclature aproved by the Saccharomyces Genome Database, cleave ApppA more readily while Aph1, the S. pombe homolog, cleaves AppppA more readily [ 20 ] . Consistent with the ApppA hydrolase activity of purified Fhit protein, most cancer cell lines that are Fhit negative at the protein level have higher levels of ApppA than cell lines that are Fhit positive [ 21 ] . Nonetheless, the actual concentrations of dinucleoside polyphosphates were submicromolar in every cell culture sample [ 21 ] and thus, under the reported culture conditions, the measured dinucleoside polyphosphates would not be expected to occupy the Fhit active site substantially [ 19 ] . Dinucleoside polyphosphate levels were measured in adenine-requiring S. cerevisiae strains before or after disruption of the Fhit-homologous HNT2 gene [ 13 ] and in adenine-requiring S. pombe strains as a function of disruption and overexpression of the Fhit-homologous aph1 gene [ 22 ] . Recently, it was observed that diadenosine polyphosphates undergo a divalent cation-dependent conformational change that might mediate their biosynthesis, catabolism or signaling properties [ 23 ] .
This conformational change results in a linear mechanical motion, with a linear movement of approximately 10 nm (Dubey et al.
In our experience, the large number of random peptides includes a broad sampling of linear and conformational protein surfaces sufficient to present at least one low affinity "complement' for any target's surface [ 19 20 ] . The immune system's antibody repertoire arises through a process [ 21 22 23 24 ] similar to in some aspects to what occurs during the panning process.
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