Words similar to conformers
Example sentences for: conformers
How can you use “conformers” in a sentence? Here are some example sentences to help you improve your vocabulary:
The optimized structures (Table 5) are very similar to those cited in Tables 2and 3, but the individual global minima are shifted to different conformers.
For example, the junction between the aptamer and the Group I ribozyme in the aptazyme Th2P6 resembled the deletion variant td ΔP6-6; the aptazyme was activated by theophylline, while the splicing defect of the deletion variant at 3 mM magnesium was suppressed by 8 mM magnesium or by stabilization of a tetraloop sequence that capped the P6 helix [ 15 ] . Defects that poise a ribozyme between active and inactive conformers have previously been used to engineer effector-dependence [ 20 ] .
Inspection of Table 4reveals that, unlike the force-field results described in Tables 2and 3, all four semiempirical recipes predict polar conformers 5 and 6 to be the low and "global" minimum energy forms, respectively, when the aqueous solvation continuum model is employed.
The final two Taxol conformers included in our dataset, 6 and 7 , appear together in the unit cell of an X-ray crystal structure determination.
Faced with a large, poly-polar organic structure and a solvation-equipped semiempirical package, the user is limited by the proposition that the aqueous solvation model might provide the correct global minimum, but that other conformers may or may not be assigned an appropriate relative energy.