Words similar to conformations
Example sentences for: conformations
How can you use “conformations” in a sentence? Here are some example sentences to help you improve your vocabulary:
Briefly, if this model is applied to Hh signaling, it proposes that, firstly, agonist and antagonists act at independent sites to select active and inactive conformations of Smo; secondly, that Smo engages an undefined coupler/effector, when it is in its signaling state; and finally, that the gain-of-function mutant form of Smo, Smo act, adopts an abnormal conformation that resembles the coupler/effector-bound signaling state of Smo with low affinity for antagonists but normal affinity for the agonist.
Examining the entire crystallized data will give the other possible conformations of the tripeptide structures in proteins.
On the basis of a simple two-state model, one might predict an increased affinity of the agonist for the mutant form, but in our studies binding of the agonist, unlike the antagonist, is not affected by the activating mutation, suggesting that a more complex model requiring two binding sites and perhaps multiple active conformations is needed to account for the observations.
Docking began with a population of random ligand conformations in random orientations and at random translations.
Multiple side chain conformations for residue positions that differ in type between the template and target proteins were generated by exploring all the possibilities in a rotamer library [ 31 ] . The most probable conformations based on the interactions of a given conformation with the local main chain were selected using an all-atom distance dependent conditional probability discriminatory function [ 32 ] .
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