Example sentences for: conformation

How can you use “conformation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The computational techniques can also provide quantitative means that can then be used to explore the relation between age and conformation of the vertebrae.

  • These data indicate that VO 2+-AMPCP was released from the conformation corresponding to species D2; however, the conformation corresponding to species D1 still had bound VO 2+-AMPCP.

  • It is tempting to speculate that, under certain conditions, the mammalian COP1 NES is shielded within the coiled-coil structure and COP1 protein is imported into the nucleus through the RING finger bridged NLS; under other conditions, probably through a conformation change of the coiled-coil domain, the NES is exposed, overwriting the NLS and transporting mammalian COP1 back into the cytoplasm.

  • The side-chain of Phe144 contacts the ligands only via its c-alpha an c-beta atoms, and similar interaction can occur with a leucine or glutamine at this position; however, while the conformation presented is projecting away from the ligands, alternative conformers could bring the side-chain closer to the agonists, and represent structural determinants for specificity.

  • Strict conformation requirements for aggregate formation can also explain interspecies transmission barriers, where prion domains of Sup35 derived from other yeast species cannot cause formation of [PSI + ] prion in Saccharomyces cerevisiae, in spite of a high degree of homology.


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