Example sentences for: cleaves

How can you use “cleaves” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A signal peptidase cleaves the signal sequence and the trimmed protein is shuttled through the Golgi for secretion.

  • In both pathways, activation of taste receptors stimulates a G protein-coupled cascade resulting in activation of phospholipase C (PLC), which cleaves phosphoinositol bisphosphate (PIP 2 ) to produce the second messengers IP 3 and diacylglycerol (DAG).

  • The endonuclease activity of DNase 1 is reduced many fold by integrating this loop from E. coli exonuclease III, but the mutant cleaves at abasic sites in DNA with low efficiency [ 29 ] . Thus additional residues in the APEs control specificity while still allowing a reasonable rate of phosphorolytic cleavage.

  • In this regard, the S. cerevisiae RNase III orthologue Rnt1p not only cleaves the 35 S rRNA precursor within the 3'-ETS [ 27 28 29 ] , but also processes snoRNA and snRNA precursors [ 30 31 32 33 ] . Further biochemical studies are required to identify the RNA targets for mammalian RNase III and to determine its involvement in RNA maturation pathways.

  • Both enzymes cleave only one DNA strand in a duplex and bacterial Xth cleaves ssDNA containing an abasic site [ 42 ] . The additional contacts huAPE1, compared to DNase 1 (Figure 6), makes 3' to the damage site and to the opposite strand lower its turnover rate and its potential to cleave normal DNA.


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