Words similar to cleaves

Example sentences for: cleaves

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Caspase 6 is activated by active Caspase 3 and in turn cleaves lamin, resulting in nuclear membrane fragmentation [ 55 ] . FAF interacts with the cytoplasmic domain of the Fas receptor to potentiate Fas-mediated apoptosis [ 56 57 ] . Thus, the up-regulated cell cycle inhibitors and apoptotic proteins clearly favor cell cycle arrest and death.
RNAseH cleaves the RNA strand in a RNA:DNA heteroduplex, but it does not cleave DNA or RNA that is not hybridized to DNA.
When diadenosine 5',5"'-( P 1, P 2-methylene- P 3-thio)- P 1, P 3-triphosphate [ 17 ] was crystallized with wild-type and mutant Fhit, the α-phosphorothioate group was found in the mutant but not wild-type active site, suggesting that α-phosphorothioate inhibitors may be slow substrates [ 12 ] . Similarly, Frey and co-workers found that Fhit slowly cleaves both R p and S p stereoisomers of γ-( m -nitrobenzyl)-adenosine 5'- O -(l-thiotriphosphate) with modest and similar beneficial effects on K m as compared to the corresponding phosphate [ 13 ] .
Both enzymes cleave only one DNA strand in a duplex and bacterial Xth cleaves ssDNA containing an abasic site [ 42 ] . The additional contacts huAPE1, compared to DNase 1 (Figure 6), makes 3' to the damage site and to the opposite strand lower its turnover rate and its potential to cleave normal DNA.
A signal peptidase cleaves the signal sequence and the trimmed protein is shuttled through the Golgi for secretion.