Words similar to cleft
Example sentences for: cleft
How can you use “cleft” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although the DPBB domain in the RNA polymerase β subunit is distorted by inserts and shows extreme sequence divergence, its role in the formation of the catalytic cleft and the spatial arrangement with respect to the more canonical DPBB of the β' subunit (Fig.
"Pierced ears, cleft chins or dimples are not currently available."
The bacterial DDRPs have two α-subunits that form a homodimer at the "base" of the β-β' dimer and stabilize the catalytic-binding cleft.
The α subunit further stabilizes this cleft, whereas the ω subunit interacts with the β' subunit [ 7 ] . Given their ubiquitous presence in all cellular life forms and high level of sequence conservation, it seems evident that the core subunits of this complex RNA synthesis machine were already present in the last universal common ancestor (LUCA) of the extant cellular life forms and performed functions mechanistically similar to those of modern DDRP.
The LBD utilizes a large hydrophobic cleft composed of residues along H3 and H5 to bind IDs [ 17 ] , and a smaller hydrophobic cleft that is composed of residues in the upper part of H3 and H5 and H12 (and corresponds to AF-2) to bind NR boxes [ 18 ] . Thus, agonists promote coregulator exchange by promoting the packing of H12 over the lower part of the ID binding region, an event that simultaneously completes the coactivator binding surface.