Example sentences for: cholesterol

How can you use “cholesterol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Overall, in the SCD children we studied, cell membrane components that are known to decrease membrane fluidity, such as cholesterol and saturated fatty acids, were associated with a low phase angle while those which increase fluidity, such as long-chain n-3 polyunsaturated fatty acids, were associated with a high phase angle.

  • Consistent with this idea, results from this study suggest that an unfavorable balance of the JNK and ERK causes the cell death observed in cholesterol oxide treated microglia.

  • We don't know exactly why; some evidence suggests alcohol--of whatever sort, by the way, not just red wine--stimulates "good" (HDL, for high density lipoprotein) cholesterol and may help prevent blood clotting.

  • StAR plays a key role in the initial steps of steroidogenesis, because it is required for transport of cholesterol to the inner mitochondrial membrane where CYP11A1 resides and the first reaction in progesterone synthesis occurs [ 45 ] . cAMP is a well known second messenger in FSH- and LH-stimulated progesterone synthesis, and a key effect of the cAMP-dependent protein kinase in GC is transcriptional control of StAR [ 46 47 ] . Estradiol is recognized as a biological amplifier of basal, FSH- and cAMP-stimulated progesterone production in pig GC, with significant synergistic effects distal to the generation of cAMP at one or more steps in cholesterol transport and metabolism [ 48 ] . Our experimental results are thus consistent with 4-AP inhibition of GC progesterone output via drug effects on multiple interacting sites in the steroidogenic pathway.

  • Microglia in the central nervous system express scavenger receptors and are involved in the oxidized LDL uptake and metabolism [ 34 ] . These cells are, thus, the macrophage-equivalent in the central nervous system [ 35 ] . Results from this laboratory showed that cholesterol oxides can cause programmed cell death in microglia [ 7 ] , which suggests that microglia, similar to macrophages, can be a potential target for oxidized LDL toxicity.


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