Words similar to choline
Example sentences for: choline
How can you use “choline” in a sentence? Here are some example sentences to help you improve your vocabulary:
The composition of the diet was as follows: 5% corn oil, 50% sugar, 20% casein, 15% cornstarch, 1% AIN-76 vitamin mix (the mix contains 20 g/kg of dl-α-tocopherol acetate), 3.5% AIN-76 mineral mix, 0.2% choline bitartrate, 0.3% D.L.
We found that the cells express exclusively PLD2 and that downregulating PLD2 expression reduces ACh synthesis, while overexpressing and/or stimulating PLD2 activity increases the synthesis of the neurotransmitter, indicating that PLD2-catalyzed hydrolysis of PC generates choline for ACh synthesis in cholinergic cells.
In the absence of PMA, overexpression of PLD2 alone increased intracellular ACh levels by 26% and choline concentrations in the medium by 57%.
In the present study, we used a cholinergic cell line, SN56 [ 17 ] , which is derived from the fusion of septal neurons of postnatal day 21 mice with N18TG2 murine neuroblastoma cells, as a model for cholinergic neurons, in order to determine the possible role of PLD 1 and PLD2 in generating choline for ACh synthesis.
These results are consistent with the hypothesis that PLD2 can generate choline for ACh synthesis in SN56 cells.