Example sentences for: choline

How can you use “choline” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The second product of PLD-catalyzed PC hydrolysis, choline, is used by all cells as a precursor of PC, and uniquely by cholinergic neurons as precursor of ACh.

  • Both PLD2 overexpression and stimulation with PMA increased PLD activity, choline production, and ACh accumulation.

  • In the presence of PMA, intracellular ACh levels and choline concentration in the medium rose further in the PLD2 transfectants reaching values more than two-fold higher than those in the control cells (Fig.

  • Treatment of a variety of cell types with phorbol esters activates PLD2 [ 6 12 18 19 ] . Thus we hypothesized that activation of PLD with PMA in SN56 cells would elevate intracellular concentrations of its product, choline, and result in increased ACh production.

  • These data show that SN56 cells express exclusively PLD2 and thus experimental manipulations of the activity of this PLD isoform were subsequently employed to determine if this enzyme is capable of producing choline for ACh synthesis in cholinergic cells.


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