Example sentences for: choline

How can you use “choline” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our previous results in cholinergic human neuroblastoma LA-N-2 cells indicated that the choline moiety from PC breakdown was released directly into the cytoplasm [ 4 ] and a kinetic study using [ 3H]choline in BHK cells also showed that choline was initially released inside the cells by PMA-activated PLD and then rapidly appeared in the medium [ 32 ] . Consistent with the latter study, we also observed a rise in the medium choline levels in SN56 cells transfected with either PLD1 or PLD2 and treated with PMA.

  • The magnitude of this effect tended to be small (approximately 15%), presumably because free choline is a rapidly turning over metabolic intermediate that does not accumulate in cells (Fig.

  • The slides were processed immunohistochemically with antisera against β-galactosidase (5 Prime → 3 Prime, Inc.) to visualize neurons labeled by Ba-Blu and choline acetyl transferase (ChAT, Chemicon, Inc.) to visualize cholinergic neurons.

  • The synthesis of the neurotransmitter acetylcholine (ACh) 1in cholinergic neurons is dependent on the availability of its precursor, choline, most of which is derived from the circulation (reviewed in [ 1 ] ) and enters cholinergic neurons via a process catalyzed by a specific transporter [ 2 3 ] . Some of the choline used for ACh synthesis is stored in membrane phosphatidylcholine (PC).

  • The latter seems unlikely due to the DHPC molecule being zwitterionic at pH 9.5, with no proton on the trimethyl-modified nitrogen of the choline.


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