Example sentences for: choline

How can you use “choline” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Concomitantly the cellular choline content was decreased by 30% both in the presence and absence of PMA by the antisense oligomer (Fig.

  • We found that the cells express exclusively PLD2 and that downregulating PLD2 expression reduces ACh synthesis, while overexpressing and/or stimulating PLD2 activity increases the synthesis of the neurotransmitter, indicating that PLD2-catalyzed hydrolysis of PC generates choline for ACh synthesis in cholinergic cells.

  • Under these conditions the choline precursor used for the synthesis of ACh is derived entirely from the intracellular pool, which includes the choline in PC [ 4 15 ] . Consistent with previous studies, treatment of the cells with PMA activated PLD (Fig.

  • Stimulation of PLD activity by PMA and the resulting increase of ACh synthesis from PLD-generated choline indicates that this pathway is regulated by PMA-responsive PKC isozymes.

  • Previous studies have shown that this choline is liberated from PC in a one-step reaction, thus indicating that it is produced by a phospholipase D (PLD, EC 3.1.


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