Words similar to cholestasis
Example sentences for: cholestasis
How can you use “cholestasis” in a sentence? Here are some example sentences to help you improve your vocabulary:
The criteria for entry into the cholestasis group were direct bilirubin >2 mg/dl (34.
• Our findings suggest that cholestasis in preterm infants receiving TPN is induced, in large part, by mechanisms that are not dependent on oxidant-mediated hepatocellular injury
Bacteria are found in the bile of the gallbladder and bile ducts [ 15 16 ] , the presence of which may have relevance to clinical diseases such as stone formation [ 19 20 21 ] , primary sclerosing cholangitis [ 22 ] , and cholestasis [ 23 24 ] . Direct exposure of sub-epithelial tissue to LPS from gram-negative bacteria causes release of cytokines by resident leukocytes and activation of macrophages [ 25 ] . The biliary fluid of patients with cholangitis has increased concentrations of the inflammatory cytokines TNF-α and IL-6 suggesting that bacterial infection leads to an increase in cytokines released into the bile [ 26 ] . Adding LPS to the bile of guinea pig gallbladders in vivo led to increased IL-1 concentration in the bile [ 27 ] . What role biliary epithelial cells play in the response to bacteria in bile is not known.
For example, lack of enteral feeding plays an important role in the development of cholestasis in the neonatal period, possibly mediated by direct hepatotoxic activity of bile salts [ 5].
Despite longer TPN courses and elevated serum transaminases, infants with cholestasis or elevated serum direct bilirubin did not display elevated urinary TBARS.
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