Example sentences for: cholestatic

How can you use “cholestatic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Animal studies using models of surgically induced extrahepatic biliary obstruction have also shown that lipid peroxidation products - specifically, malondialdehyde (MDA) - are increased in the cholestatic liver [ 8, 9].

  • Although Still's disease can rarely lead to hepatic involvement with cholestatic hepatitis, the prior history of rheumatoid factor seropositivity and a low serum ferritin level made this diagnosis unlikely [ 21 ] . Granulomatous hepatitis with marked elevations in serum alkaline phosphatase and granulomas on liver biopsy have been reported in patients with SSZ hepatotoxicity [ 22 23 24 ] . Although liver tissue was not obtained in our patient, the predominance of serum alkaline phosphatase and bilirubin level elevations and the presence of granulomas in other tissues suggest that she probably had granulomatous hepatitis.

  • Some studies have suggested that excessive amino acids, hepatotoxic bile acids, bacterial overgrowth, sepsis, micronutrient deficiency, and TPN contaminants all contribute to cholestatic liver injury [ 4, 5, 6].

  • While inflammation is an important element in the defense against infection, it can also contribute to cholestatic biliary diseases and cholelithiasis.

  • Our patient had severe cholestatic hepatitis with coagulopathy.


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