Words similar to cftr

Example sentences for: cftr

How can you use “cftr” in a sentence? Here are some example sentences to help you improve your vocabulary:

Active rates of taurocholate uptake were twice as high in the heterozygous cftr (+/-) mice (n = 23) compared to wild-type mice (n = 6) (average of all data points in the terminal ileum 109 ± 8 vs. 64 ± 13 cm pmol/mm 2; p < 0.05) and fourfold higher in the homozygous cftr (-/-) mice (n = 6) (212 ± 32 pmol/mm 2; p < 0.05 vs. wild-type).
Contrary to these findings, other investigations have been unable to demonstrate any changes in sodium/glucose co-transport when examining brush border membrane vesicles [ 28 ] . The up-regulation of intestinal sodium-linked nutrient absorption by cftr may occur via a mechanism that does not involve changes of the brush border membrane but rather intracellular components [ 28 ] . Intestinal sodium-linked nutrient absorption would then be undetectable in brush border membrane vesicle studies.
Of course, a more widespread perturbation of ion channel regulation in the absence of CFTR is also a possibility, as CFTR has been demonstrated to be a master regulator of such diverse proteins as the Na/K pump [ 41 ] , the basolateral Na/K/2Cl co-transporter [ 42 ] , and the inducible nitric oxide synthase [ 43 ] .
In addition, IBAT may be yet another apical membrane transport protein that is regulated by CFTR.
Cftr knockout mice, with targeted disruption of the cftr gene created at the University of North Carolina [ 13 ] , were maintained at the University of Washington Animal Care Facility under the auspices of the UW Cystic Fibrosis Research Center.