Example sentences for: cftr

How can you use “cftr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Wild-type mice expressed cftr protein by immunoblotting, while cftr (-/-) did not [ 14 ] . All chemicals were from Sigma unless otherwise stated (Sigma-Aldrich, St. Louis, MO).

  • Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding the CFTR chloride channel [ 1 ] . CFTR is known to possess multiple cellular functions beyond its role as an apical membrane chloride channel [ 2 ] . For example, regulation of other ion channels, such as the epithelial sodium channel and the outwardly rectified chloride channel, are well-described functions of CFTR [ 3 4 ] . Numerous other functions, such as regulation of intracellular vesicular pH, regulation of membrane recycling, and regulation of mucin exocytosis are less firmly established.

  • Increased bile acid transport in cftr (-/-) mice is associated with an increase in the abundance of IBAT protein in the brush border membrane.

  • The ΔF508 mutation is the most common genetic disturbance affecting the CFTR gene.

  • The oligonucleotide target contained the sequence for the M1101K locus of the CFTR gene, a disease-causing mutation.


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