Example sentences for: centrosomal

How can you use “centrosomal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Examples include the polarized localization of oocyte mRNAs which is crucial for the establishment axis formation in the embryo [ 1 2 3 ] , the targeting of specific mRNAs to the synapses of nerve cells [ 4 5 ] , centrosomal segregation of mRNAs in the mollusk embryo which results in asymmetric inheritance [ 6 ] and the localization of β-actin mRNA to sites of active actin polymerization at the leading edge of motile fibroblasts [ 7 8 ] . In each of these cases, mRNA targeting is mediated by the cytoskeleton.

  • The nuclear lamins contain short, conserved sequences flanking the lamin rod domain, which are phosphorylated by cdc2 kinase [ 41 ] . The 90 amino acid PACT domain, which immediately follows the coiled-coil domain of the related proteins pericentrin and AKAP450 and two uncharacterized coiled-coil open reading frames from Drosophila and Schizosaccharomyces pombe , confers centrosomal localization [ 19 ] . A conserved domain of ca. 50 amino acids was found in several Golgi-associated large coiled-coil proteins.


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