Example sentences for: centromeres

How can you use “centromeres” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • First, the Rad26-GFP dots were resistant to an extraction method that was developed to specifically-preserve the localization of chromatin-binding proteins [ 42 ] . Secondly, we discovered that the rad26Δ strain is sensitive to TBZ, a phenotype common to mutants that disrupt centromeric-heterochromatin [ 45 ] . Finally, fission yeast has a relatively small number of heterochromatic regions (3 centromeres, 6 telomeres, and 1 mating-type locus; [ 53 54 ] ) and the number of Rad26-GFP dots we observe is roughly consistent with localization to these regions.

  • We identified 0.9 Mb of repeated sequence (less than 1% of the euchromatic genome), 40% mapping to chromosome X, 40% to chromosome 2, 15% to chromosome 3 and 3% to chromosome 4. Although there are more repeats on chromosomes X and 2, they appear to be randomly distributed and are not clustered at the centromeres or telomeres.

  • For instance, cohesin in chromosome arms may help to organize or condense chromosomes, whereas cohesin at centromeres may be more directly involved in chromosome bi-orientation at the spindle and segregation.

  • Differences between Arms and Centromeres

  • In animals, heterochromatin is typically found near centromeres and other regions of low sequence complexity.


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