Words similar to centromeric
Example sentences for: centromeric
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The gene encoding the amyloid precursor protein-binding protein A2 ( APBA2 ) was previously mapped to chromosome 15 [ 20 ] and localized to the common PWS/AS deletion region centromeric to BP3 and distal to a cluster of GABA A receptor subunit genes [ 21 22 ] (see Figure 1).
Human chromosome DNA specific to alpha-satellite centromeric regions was also obtained from the ATCC [catalog numbers: 61078 (D9Z3, chromosome 9); 61396 (D10S71, chromosome 10); 65438 (D11Z1 chromosome 11); 61398 (D12Z1, chromosome 12) and 65442 (D17Z1, chromosome 17).
The length of centromeric alphoid arrays of different human chromosomes varies from 0.2 to 5 Mb.
Physiological experiments can also be used to characterize heterochromatin-binding proteins [ 45 ] . For example, absence of Swi6 in fission yeast sensitizes cells to thiabendazole (TBZ), a microtubule depolymerizing drug [ 46 ] . Presumably this occurs because absence of Swi6 disrupts centromeric heterochromatin and, as a result, sensitizes cells to drugs that compromise spindle function.
Centromeric probe signal was readily demonstrable using biotinyl-tyramide based in situ hybridization (Figure 2D).