Words similar to cell-mediated
Example sentences for: cell-mediated
How can you use “cell-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Type 1 diabetes mellitus (T1DM) is a T cell-mediated autoimmune disease characterized by lymphocytic infiltration of the pancreatic islets of Langerhans with subsequent destruction of the insulin-producing beta cells [ 1 ] . Non-obese diabetic (NOD) female mice, a murine model for T1DM, spontaneously develop diabetes by 30 weeks-of-age, with infiltrating cells appearing around the pancreatic islets as early as at 3-4 weeks-of-age [ 2 ] .
Other factors that may contribute include functional defects in antigen-specific cell-mediated immunity [35,37,40,41,42], and progressive immune escape [43,44,45].
SLC/CCL21, a CC chemokine expressed in high endothelial venules and in T cell zones of spleen and lymph nodes, strongly attracts naive T cells and DCs [ 1 2 3 4 5 6 7 8 ] . Because DCs are potent APCs that function as principal activators of T cells, the capacity to facilitate the co-localization of both DC and T cells may reverse tumor-mediated immune suppression and orchestrate effective cell-mediated immune responses [ 9 10 25 26 27 ] . In addition to its immunotherapeutic potential, SLC/CCL21 has been found to have potent angiostatic effects [ 28 ] , thus adding further support for its use in cancer therapy.
Qualitative comparable central projections are found in wildtype control littermates (data not shown) and suggest that the central projection to cochlear nuclei is at least until P8 in mice not critically dependent on auditory information or other hair cell-mediated influences, in agreement with recent suggestions [ 5 19 ] .
These factors include abnormalities in humoral and cell-mediated immunity, phagocytic cell dysfunction, and skin and mucous membrane defects [ 3 ] . The presence of neutropenia [ 4 5 ] use of central venous catheters [ 4 6 ] , low CD4 +lymphocyte count, and intravenous drug use [ 6 ] are cited as risk factors for bacteremic infections in patients with HIV infection.
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