Example sentences for: cell-mediated

How can you use “cell-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • T helper epitopes have become common components of synthetic vaccine constructs due to their ability to provide immunological help for both humoral and cell-mediated responses [ 11 14 15 16 ] . T cell epitopes that can induce helper activity by binding to a wide range of HLA-DR alleles have been developed by a number of investigators using various antigen systems [ 17 18 19 ] . T cell epitopes that have the property of binding across a wide range of HLA-DR haplotypes are necessary for the construction of synthetic vaccines that would be useful in the human population as a whole.

  • There is accumulating evidence that, in addition to activation-induced cell death or anergy, T-cell-mediated dominant control of self-reactive T cells represents one mechanism for maintaining immunological tolerance [ 1 2 3 ] . Studies conducted in a number of experimental models have demonstrated the existence of regulatory T-cell subsets that prevent activation of autoreactive T cells.

  • These factors include abnormalities in humoral and cell-mediated immunity, phagocytic cell dysfunction, and skin and mucous membrane defects [ 3 ] . The presence of neutropenia [ 4 5 ] use of central venous catheters [ 4 6 ] , low CD4 +lymphocyte count, and intravenous drug use [ 6 ] are cited as risk factors for bacteremic infections in patients with HIV infection.

  • We suggest that the combinatorial approach presented here merits consideration in the design of clinical trials aimed to achieve T cell-mediated anti-tumor immunity.

  • Qualitative comparable central projections are found in wildtype control littermates (data not shown) and suggest that the central projection to cochlear nuclei is at least until P8 in mice not critically dependent on auditory information or other hair cell-mediated influences, in agreement with recent suggestions [ 5 19 ] .


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