Example sentences for: cell-cycle

How can you use “cell-cycle” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Based on studies involving compounds that alter microtubular kinetics and induce both cell-cycle delay and aneuploidy, several groups have proposed that temporal perturbations during mammalian oocyte maturation (OM) predispose oocytes to aneuploidy [ 3 4 5 6 ] . In addition to faulty microtubule kinetics, perturbations during OM may also stem from abnormal function of centrosomes, kinetochores, spindle checkpoints proteins, the anaphase-promoting complex (APC), the securin-separin-cohesion complex proteins, and the proteasome [ 7 ] .

  • We analyzed the cell-cycle-related genes selected by Spellman et al . [ 23] to demonstrate the relationship between cell-cycle phases and gene-expression patterns and to select a subset of genes that show the highest and most reproducible variance across the cell-cycle phases.

  • Figure 3shows a biplot of the 773 gene scores and the five cell-cycle phase group loadings.

  • As illustrated by Figures 3and 4, in the cell-cycle phase M/G1, CDC46 (encoding part of the replication complex) was selected as an upregulated gene, whereas the histone genes HTB2, HTA2 and HHO1 (also marked by Spellman et al . [ 23] and Fellenberg et al . [ 14]) were selected as downregulated genes.

  • Genes without variance with respect to the cell cycle (equally transcribed in most cell-cycle phases) would lie in the middle of the biplot.


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