Words similar to cell-cell
Example sentences for: cell-cell
How can you use “cell-cell” in a sentence? Here are some example sentences to help you improve your vocabulary:
Whether it functions in the processing of androgen-induced secretory proteins or in other pathways induced by androgens or perhaps even in cell-cell signaling is unclear, but the degree of induction suggests it may have an important role in prostatic physiology.
Environmental factors such as cell-cell contact and hypotonicity might place additional demands on the equatorial contractile apparatus that go beyond the intrinsic stiffness of the cell cortex.
To investigate further the role of Notch-mediated cell-cell signaling in vertebrate neural development we have tested neural pattern formation in zebrafish embryos.
Recently, a subset of CD4 +T cells was identified that is present on 5-10% of CD4 +T cells in normal naïve mice and expresses CD25 (the α-chain of IL-2 receptor) [ 4 5 ] . Functional analysis of murine CD4 +CD25 +T cells showed that those cells, which constitutively express cytotoxic T-lymphocyte antigen (CTLA)-4 [ 6 7 8 ] , fail to proliferate or secret cytokines in response to polyclonal or antigen-specific stimulation, but inhibit the activation of conventional responsive T cells [ 1 2 3 8 9 ] . The suppressive activity of the CD4 +CD25 +T cells depends on signaling via the negative regulator of T-cell activation CTLA-4 [ 7 ] and requires a cell-cell interaction that possibly involves cell surface bound transforming growth factor (TGF)-β 1 [ 1 10 ] . It has been shown that B7/CD28 costimulation is essential for the development and homeostasis of the CD4 +CD25 +regulatory T cells [ 6 ] , which play critical roles not only in preventing autoimmunity but also in controlling tumor immunity and transplantation tolerance [ 2 11 ] .
IL-2 has direct effects on immune cells carrying the IL-2 receptor, which in turn release soluble factors and/or activate other cells by cell-cell interactions.
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