Words similar to cell-autonomous
Example sentences for: cell-autonomous
How can you use “cell-autonomous” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the Hoxa3,Pax1 compound mutants, cell-autonomous TEC defects cause a partial block at the DN-DP transition, so thymocytes do progress to DP and SP stages, albeit at reduced frequencies [ 29 ] . TEC defects are seen as early as E12.
Because of the complex interdependence of TEC and thymocyte differentiation, defects in fetal TEC development can be caused either directly by cell-autonomous TEC differentiation defects, or indirectly by defective thymocyte maturation.
Expression patterns in cultured labial skin fibroblasts derived from two different individuals with AR mosaicism suggested that the cell-autonomous AR status was a relevant determinant of baseline gene expression in genital skin fibroblasts.
We have observed consistent and characteristic differences in the gene-expression patterns of skin fibroblasts derived from different locations on the body [ 11 ] . However, the current set of experiments suggests that the androgen receptor has a cell-autonomous role which contributes to a stable androgen-independent gene-expression pattern in genital fibroblasts.
We also analyzed two mutant strains that have either cell-autonomous ( Hoxa3 +/- Pax1 -/-) or non-cell-autonomous ( Rag1 -/-) TEC defects, with blocks at different stages of thymocyte differentiation.