Example sentences for: ccrm
How can you use “ccrm” in a sentence? Here are some example sentences to help you improve your vocabulary:
They worked their way through 1,000 inhibitor candidates, ending up with a small subset—no more than about 20—that not only inhibited CcrM, but also killed
The researchers designed adenine-like molecules that would bind to CcrM and then developed inhibitors.
They didn't know the structure of CcrM, Benkovic explains, but the literature about other methyltransferases suggested that the adenine molecule, which is the substrate for CcrM within DNA, binds to a specific region of the enzyme.
Their first candidate was an essential enzyme, a methyltransferase called CcrM, that prevents a particular piece of DNA from being expressed in a cell by tagging it with a methyl group.