Example sentences for: ccl

How can you use “ccl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Representative images of tissue sections from control and treated tissues are shown in Figure 1. Examples of processed sample image tiles are shown in Figure 2, where a control liver (Figure 2a) can be compared to a treated liver (Figure 2b), illustrating the significant structural damage induced by treatment with CCl 4 . Gene-expression profiles were generated from the same livers using DNA microarrays.

  • While most cytokine research has focused on cells of the immune system, other cell types produce cytokines including the epithelial cells of the lung [ 28 29 ] , retina [ 30 ] , and intestines [ 31 32 ] . Among the few studies involving the biliary system, it was demonstrated that cultured human intrahepatic duct epithelial cells produce functional IL-8 and MCP-1 (CCL2) [ 14 33 ] . Isolated human intrahepatic epithelial ducts expressed immunoreactive IL-6 when treated with IL-1β or phorbal myristate acetate [ 34 ] . Intracellular TNF-α mRNA and protein was detected in intrahepatic biliary duct cells in tissue sections [ 35 ] , but not in cultured intrahepatic epithelial cells; therefore, there was no clear demonstration that biliary epithelium secretes TNF-α.

  • This is an ADAM10-homolog known to be a tumor necrosis factor-α (TNFα) convertase [ 21 ] , TNFα produced by Kupffer cells in the liver stimulates production of TNFα, a mitogen for hepatocytes helping to generate new cells needed to rebuild damaged areas of the liver [ 22 ] . Kupffer cells have a significant role as mediators of acute inflammation after CCl 4 treatment; however, they also produce factors that can cause secondary injury in the liver through fibrogenic responses.

  • Based on these dual capacities, we as well as others have begun pre-clinical evaluation of SLC/CCL21 in several tumor models [ 9 10 25 26 27 ] .

  • The murine fibroblast NIH 3T3 cell line (CCL 92) and the amphotropic retroviral packaging cell line PA317 (CRL 9078) were obtained from the American Type Culture Collection (Rockville, MD, USA).


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