Example sentences for: ccl

How can you use “ccl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • SLC/CCL21 is documented to have direct anti-angiogenic effects [ 28 29 ] ; the tumor reductions observed in this model could have been due to participation by T cells secreting IFNγ leading to inhibition of angiogenesis via MIG/CXCL9 and IP-10/CXCL10, as well as T cell-dependent immunity [ 16 ] . IFNγ mediates a range of biological effects that facilitate anticancer immunity.

  • Compared to SLC/CCL21-treated mice receiving control antibody, flow cytometric evaluation of single-cell suspensions of non-necrotic tumors from SLC/CCL21-treated mice receiving neutralizing antibodies to MIG/CXCL9, IP-10/CXCL10 and IFNγ showed 10, 12 and 31 % decreases, respectively, in the gated CD3 CXCR3 +veT cell populations (Table 1).

  • This study demonstrates the expression of available chemokine binding sites for CCL2, CCL3, CCL5 and CXCL8 on CD68 +macrophages in the subintimal and intimal layers of rheumatoid and nonrheumatoid synovia.

  • Thus, an increase in IFNγ at the tumor site of SLC/CCL21-treated mice could explain the relative increases in IP-10/CXCL10 and MIG/CXCL9.

  • Our results suggest that the anti-tumor properties of SLC/CCL21 may be due to its chemotactic capacity in co-localization of DC and T cells as well as in part to the induction of key cytokines such as IFNγ, IP-10/CXCL10 and MIG/CXCL9.


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