Example sentences for: blosum

How can you use “blosum” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 3. Maximum likelihood pairwise distance matrices are calculated for each of the x multiple alignments using a model of amino acid substitution (for example, BLOSUM [ 25 ] or Dayhoff PAM [ 26 ] ).

  • The resultant six partial alignments were then combined by using with the profile alignment procedure of ClustalX [ 57 ] with the Blosum100 scoring matrix.

  • For all three possible unrooted tree topologies maximum-likelihood values and posterior probabilities were calculated using in-house JAVA programs that were written utilizing classes from the Phylogenetic Analysis Library version 1.0 [ 54 ] and parts of Vanilla package version 1.0 [ 54 ] . If not indicated otherwise, likelihood values were estimated using the automatically selected suitable substitution model (chosen from BLOSUM62, CPREV, Dayhoff, JTT, MTREV24, VT and WAG) with no ASRV.

  • The recommended value of 5.0 times the residue diversity was used for the total number of pseudo-counts, and the amino acid substitution probabilities were taken from the BLOSUM 62 matrix [ 22 ] . A substitution matrix based on transmembrane helices [ 23 ] was also used in some cases, however, the results were not altered substantially.

  • The default matrix (BLOSUM62) and gap cost were used but a filter was not used in these searches.


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