Example sentences for: beta-catenin-independent

How can you use “beta-catenin-independent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • PMA, a phorbol ester, activates PKC and has previously been shown to activate SL-1 [ 40 ] . It appears that mesothelin is activated by Wnt-1, which can be mimicked by LiCl, and that SL-1 is activated by Wnt-5a in a beta-catenin-independent manner, which can be mimicked by activating PKC.

  • The ability of dnWnt-11 to block expression of some genes in Xenopus [ 6 ] and the ability of Wnt-5a to activate the Ca 2+sensitive transcription factor nuclear factor of activated T cells (NFAT) [ 14 ] , support the likelihood that Wnt-5a can regulate gene expression through a beta-catenin-independent mechanism.


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