Example sentences for: beta-cell

How can you use “beta-cell” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Among beta-cell autoantigens, GAD65 is an important initial target of the immune response that results in beta-cell destruction and diabetes, in both humans and NOD mice [ 6 7 8 9 ] . While both humoral and cellular responses to GAD65 occur as early as 4 weeks of age in NOD mice [ 8 ] , there is considerable evidence that beta-cell-specific T H 1 cells are the effectors of T1DM, whereas T H 2 cells appear to have a protective role [ 10 ] . Accordingly, a shift of the autoimmune response from T H 1 to T H 2 predominance has represented a promising strategy for prevention of diabetes and other T H 1-mediated autoimmune diseases.

  • These patients develop diabetes when tissues of the body fail to utilize glucose appropriately owing to increased resistance to insulin and concomitant beta-cell dysfunction of the pancreas [16].

  • Progression of disease is also attributed to worsening beta-cell dysfunction and decreased release of insulin [26].

  • Insulin sensitivity (%S) and beta-cell function (%B) were estimated based on the Homeostasis Model Assessment (HOMA) as described elsewhere [ 38, 39].


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