Example sentences for: bcr

How can you use “bcr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In contrast, PLCγ2 was rapidly and highly phosphorylated after stimulation of BCR (lanes 5 and 8).

  • Polyclonal rabbit anti-IgM antibodies were used to signal BCL 1 .3B3 through the BCR [ 27 ] . Polyclonal rabbit anti-ovalbumin was used as a negative control for activation and immunoprecipitation experiments.

  • The increase in Syk activity in response to BCR engagement in BCL 1 .3B3 was accompanied by an increase in tyrosine phosphorylation of Syk protein in cells (Figure 2C).

  • Stimulation through the BCR has been shown to induce changes in cell growth and viability in several B cell systems, including the human Daudi, chicken DT40 and mouse WEHI-231 and BCL 1 .3B3 B cell lymphomas [ 12 19 27 38 51 52 53 ] . For example, stimulation of BCL 1 .3B3 through the BCR suppressed exponential population growth in cell culture (Figure 1A).

  • However Btk:ER was clearly able to induce sustained ERK activity and this, coupled with the findings that in Btk-deficient cells the sustained response is impaired [ 9], suggest that Btk activation may be responsible for the prolonged ERK activation normally detected following BCR cross-linking.


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