Words similar to bcr
Example sentences for: bcr
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In contrast, PLCγ2 was rapidly and highly phosphorylated after stimulation of BCR (lanes 5 and 8).
Polyclonal rabbit anti-IgM antibodies were used to signal BCL 1 .3B3 through the BCR [ 27 ] . Polyclonal rabbit anti-ovalbumin was used as a negative control for activation and immunoprecipitation experiments.
The increase in Syk activity in response to BCR engagement in BCL 1 .3B3 was accompanied by an increase in tyrosine phosphorylation of Syk protein in cells (Figure 2C).
Stimulation through the BCR has been shown to induce changes in cell growth and viability in several B cell systems, including the human Daudi, chicken DT40 and mouse WEHI-231 and BCL 1 .3B3 B cell lymphomas [ 12 19 27 38 51 52 53 ] . For example, stimulation of BCL 1 .3B3 through the BCR suppressed exponential population growth in cell culture (Figure 1A).
However Btk:ER was clearly able to induce sustained ERK activity and this, coupled with the findings that in Btk-deficient cells the sustained response is impaired [ 9], suggest that Btk activation may be responsible for the prolonged ERK activation normally detected following BCR cross-linking.
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