Words similar to bcr
Example sentences for: bcr
How can you use “bcr” in a sentence? Here are some example sentences to help you improve your vocabulary:
To determine if expression of the (K395A/3F)Syk mutant resulted in a change in BCR responsiveness, the kinetics of Syk activation were measured in clones 2.1.
Examples include A6 kinases [ 17], a number of lipid kinase family members [ 18], aminoglycoside phosphotransferases [ 19], pyruvate dehydrogenase kinase family members [ 20], DNA-dependent protein kinase [ 21], ATM [ 22], ATR [ 23], BCR [ 24, 25], a transient receptor potential channel [ 26] and actin-fragmin kinases [ 27].
Apoptosis is a major biological response of B cells to BCR cross-linking and Btk is clearly necessary for this effect in DT40 cells [ 12, 13].
In syk -deficient DT40 cells, BCR induced apoptosis was abrogated indicating that Syk was necessary for this cellular response [ 38 ] . Having established cells with constitutive Syk activity, it was now possible to establish if Syk activation is sufficient for any of the signaling responses.
However, in the context of signaling through the BCR, we surprisingly found that kinase inactive Btk:ER could reconstitute calcium mobilization in these Btk-deficient cells (Fig 2C).