Words similar to bcl-

Example sentences for: bcl-

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Negative controls were carried out without primary antibodies and with primary antibodies preabsorbed (100-fold molar excess, 2 h, 25 C) with an 8-oxoguanine oligonucleotide (3850-100-01; Trevigen), human recombinant p53 (Santa Cruz Biotechnology, Santa Cruz, CA), Bcl-2 peptide (amino acids 41-54; StressGen), or recombinant polymerase β (Trevigen).
Akt directly phosphorylates and inactivates the pro-apoptotic proteins ASK1, BAD, caspase 9 [ 21 22 23 24 ] . Akt also induces the expression of the anti-apoptotic Bcl-2 and c-FLIP proteins, and suppresses the cell cycle inhibitor p27 KIP [ 25 26 27 28 ] . This later effect is via the phosphorylation and inactivation of the forkhead family of transcription factors AFX, FKHR and FKHR-L1.
Stable SW-1353 cell lines carrying a pBkRSV vector with a Bcl-3 expression insert were created as described previously [ 24 ] . Freshly excised, macroscopically normal cartilage and synovium from OA patients undergoing knee replacement surgery were obtained from a local orthopedic unit (Dartmouth Hitchcock Memorial Hospital, Lebanon, NH, USA).
Bcl-2 (NM_009741); forward primer: 5'-CGGAGACGAGTTCAACGAAAC-3'(681-701); reverse primer: 5'-TGTAAGATAACCATTTGAGGGTGG-3'(770-747).
Bcl-2 impedes the subcellular trafficking of p53, inhibits downstream adapters necessary for stimulation of the apoptotic caspases, and can act as an antioxidant [ 15 28 ] .