Words similar to bcl-

Example sentences for: bcl-

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Recent work has shown that the Bcl-2 family regulates mitochondrial homeostasis during apoptosis [ 1 ] . Pro-apoptotic members, including Bax, Bak, Bid, and Bim, promote the release of death-inducing proteins, such as cytochrome c [ 2 3 ] , smac [ 4 ] , and endonuclease G [ 5 ] , from mitochondria while anti-apoptotic members, such as Bcl-2 and Bcl-X L , inhibit this release.
Mcl-1 is an anti-apoptotic member of the Bcl-2 family whose expression is correlated with decreased apoptosis and increased survival in human neutrophils [ 15 16 ] . Western blot analysis showed that neutrophils from control animals did not express Mcl-1 protein (Fig.
Similar patterns emerged for MMP-13 (63%, 81%, and 99%) and Bcl-3 (33%, 61%, and 86%) in response to the respective doses of CDDO, all results being significant.
For example, the TNF/TNF receptor-signaling complex activates caspase 8, which leads to the activation and cleavage of Bid, a proapoptotic protein of the Bcl-2 family.
Alterations in p53 were related to accretions of apoptotic/internucleosomal DNA cleavage sites [ 13 ] , the oxidative DNA stress marker 8-oxoguanine [ 14 ] , the survival protein Bcl-2 [ 15 ] , and base-excision repair polymerase β [ 16 ] . Corpora lutea were evaluated for progesterone and steroidogenic cell and vascular compositions.