Example sentences for: bcl-

How can you use “bcl-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To examine further the role of Bcl-3 in IL-1-induced MMP-1 and MMP-13 expression, we used SW-1353 cells stably transfected with a Bcl-3 expression construct.

  • Bcl-2 impedes the subcellular trafficking of p53, inhibits downstream adapters necessary for stimulation of the apoptotic caspases, and can act as an antioxidant [ 15 28 ] .

  • Dysfunction of voltage dependent anion channel opening, ADP/ATP exchange, the electron transport chain, oxidative phosphorylation, and calcium buffering through the action of this family of proteins have been reported [ 6 7 8 ] . While early defects in the electron transport chain can be reversed by addition of exogenous cytochrome c, the damage eventually becomes refractory to cytochrome c addition [ 8 ] . This finding suggests that pro-death Bcl-2 proteins can damage mitochondrial function independent of cytochrome c loss.

  • We were also unable to detect Bax or Bcl-X L in rat adherent vascular lung neutrophils, which is in contrast to results with human peripheral blood neutrophils [ 30 31 ] . These differences may be due to unique attributes of human and rat cells, their distinct location in the vasculature, and/or to their exposure to inflammatory stimuli in vivo .

  • Furthermore, the presence of exogenous Bcl-3 sustained MMP-1 expression in the presence of CDDO in comparison with cells expressing empty vector.


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