Words similar to bcl

Example sentences for: bcl

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Most significantly, a mixture of a lysate from unstimulated BCL 1 .3B3 cells harbouring wildtype Syk with a lysate from unstimulated DT40 expressing the K395A, 3F mutant Syk (see below), at 1:5, 1:1 and 5:1 ratios, showed no activity in the immune complex kinase assay (data not shown).
Among the 4 apoptosis-regulating genes, bcl2, caspase 3 and DRAK2 are all induced by IL-2, while the expression of Toso is suppressed.
3 - 5 × 10 6BCL 1 .3B3 cells and infectants were stimulated with 15 μg of affinity purified rabbit anti-mouse IgM or anti-ovalbumin antibody at 37°C for 30 sec (unless otherwise specified).
This result indicates that the constitutive Syk activity identified in BCL 1 .3B3 clones expressing (K395A/3F)Syk was likely due to endogenous Syk and not the (K395A/3F)Syk mutant.
Syk has also been implicated in BCR-induced apoptosis found in the chicken B lymphoma line, DT40 [ 38 ] . To determine the role of Syk kinase activation in the apoptotic response in BCL 1 .3B3, overexpression of a mutant form of Syk was used in an effort to alter the level of Syk activation following BCR engagement.