Words similar to bcl

Example sentences for: bcl

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Syk has also been implicated in BCR-induced apoptosis found in the chicken B lymphoma line, DT40 [ 38 ] . To determine the role of Syk kinase activation in the apoptotic response in BCL 1 .3B3, overexpression of a mutant form of Syk was used in an effort to alter the level of Syk activation following BCR engagement.
Polyclonal rabbit anti-IgM antibodies were used to signal BCL 1 .3B3 through the BCR [ 27 ] . Polyclonal rabbit anti-ovalbumin was used as a negative control for activation and immunoprecipitation experiments.
BCR-mediated tyrosine kinase activation is thought to be involved in the signal transduction cascades that give rise to these changes in cell growth and viability [ 19 ] . To determine if BCR engagement under these conditions leads to Syk kinase activation, increasing amounts of anti-IgM were added to cultured BCL 1 .3B3 cells.
BCR-mediated apoptosis was preceded by an increase in Syk kinase activity in BCL 1 .3B3.
The increase in Syk activity in response to BCR engagement in BCL 1 .3B3 was accompanied by an increase in tyrosine phosphorylation of Syk protein in cells (Figure 2C).