Words similar to bcl

Example sentences for: bcl

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BCL 1 .3B3 cells were infected with defective retroviruses expressing wildtype or (K395A/3F) mutant Syk.
Syk has also been implicated in BCR-induced apoptosis found in the chicken B lymphoma line, DT40 [ 38 ] . To determine the role of Syk kinase activation in the apoptotic response in BCL 1 .3B3, overexpression of a mutant form of Syk was used in an effort to alter the level of Syk activation following BCR engagement.
Syk activity was measured in parental BCL 1 .3B3 (Figure 3D, lanes 1-3) and cells that express the (K395A/3F)Syk molecule (lanes 4 - 15).
To determine if the constitutive phenotype was a result of the specific mutations introduced or if overexpression of a full-length Syk molecule was sufficient to give high basal kinase activity, Syk activity was analyzed from BCL 1 .3B3 cells that expressed a wildtype human Syk transgene (Figure 6).
In unstimulated and control treated BCL 1 .3B3 cells (lanes 1 and 6), low, basal levels of Syk activity were detected.