Words similar to bcr-induced

Example sentences for: bcr-induced

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Btk-deficient B cells are defective in BCR-induced PLCγ2 phosphorylation and calcium mobilization [ 8, 11].
These data are in agreement with previous reports that document the requirement for PLCγ2 in BCR-induced JNK activation [ 38].
In particular, we have found that Btk-deficient DT40 cells reconstituted with Txk, an atypical Tec family PTK, fail to undergo BCR-induced JNK activation (Tomlinson and Johnston, unpublished data) and apoptosis [ 13], but ERK activation is relatively normal [ 13].
In addition, we have found that kinase inactive Btk can reconstitute BCR-induced ERK MAPK activation, but not PLCγ2 phosphorylation (Tomlinson, Bolen and Johnston, unpublished data).
Previous studies have implicated Syk in BCR-induced apoptosis in other cell lines [ 37 38 ] . To examine the putative role of Syk in BCR-induced apoptosis and cell cycle arrest in BCL 1 .3B3, we attempted to alter Syk activity through the expression of mutant forms of Syk.