Words similar to bcr-induced

Example sentences for: bcr-induced

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BCR-induced interaction between Cbl and Syk increases the susceptibility of Syk to proteolysis [ 55 ] , possibly through enhancement of ubiquitination [ 56 ] . Expression of a dominant-negative SHP-1 phosphatase in the mature murine B cell line K46 resulted in an increase in BCR-induced Syk kinase activity as measured by C3b phosphorylation in an ICKA and enhanced BCR-induced Ca 2+fluxes [ 57 ] . It remains to be determined if interference with any of these known regulatory proteins is responsible for the dominant-positive effect.
The mechanism by which 4-HT activates Btk:ER is not known, but may be different to the mechanism of BCR-induced activation, since the two stimuli induce phosphorylation on different sites.
These data are in agreement with previous reports that document the requirement for PLCγ2 in BCR-induced JNK activation [ 38].
Previous studies have implicated Syk in BCR-induced apoptosis in other cell lines [ 37 38 ] . To examine the putative role of Syk in BCR-induced apoptosis and cell cycle arrest in BCL 1 .3B3, we attempted to alter Syk activity through the expression of mutant forms of Syk.
This is consistent with reports that PLCγ2 is necessary for BCR-induced apoptosis [ 37].