Example sentences for: autoimmunity

How can you use “autoimmunity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A controlled balance between initiation and downregulation of immune responses (peripheral tolerance) is important for maintaining immune homeostasis, whereas dysfunctional immune regulation may lead to chronic inflammation or autoimmunity [ 29 ] . The CD4 +CD25 +regulatory T cells have been shown to suppress autoimmunity in several animal models [ 2 ] . To evaluate the role of the CD4 +CD25 +regulatory T cells in PGIA, three approaches were used.

  • Taken together with the findings reported herein, this work indicates that anaphylactic reactions can be elicited in mice that have been immunized with pancreatic islet-associated self-peptides that also represent significant targets of autoimmunity in T1DM.

  • This hypothesis predicts that females with autoimmunity may be particularly prone to this mechanism of `inadequate tolerization' by virtue of extremely skewed X-chromosome inactivation.

  • Other markers of systemic inflammation or autoimmunity did not correlate with the presence or absence of LFT abnormalities.

  • The inheritance of certain polymorphisms of the mannose-binding lectin gene on Ch10 in persons with CVID are associated with earlier age of onset of manifestations of antibody deficiency and with increased risk of autoimmunity [ 25 ] . Altogether, these observations are consistent with the hypothesis that many common heritable antibody deficiency phenotypes collectively diagnosed as CVID or IgGSD are the result of the inheritance of multiple disease-predisposing alleles on Ch6p and possibly other chromosomes.


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