Words similar to autoimmunity

Example sentences for: autoimmunity

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Simple and accurate methods exist to determine for a single pair of alleles how the three possible genotypes (2 homozygotes and one heterozygote) affect disease outcome, and these methods have been used frequently in the literature on autoimmunity and HLA [ 28 29 30 ] and once (to our knowledge) in the HLA-infectious disease literature [ 33 ] . It is of additional interest for epidemiologists, immunologists, vaccine designers and evaluators, and population geneticists to know whether HLA heterozygosity in general improves the immune response to and outcome of infectious diseases.
Second, if this actually leads to autoimmunity, it also predicts that the initial break in tolerance that leads to disease should involve an X-linked autoantigen that is expressed in a peripheral nontolerizing site or circumstance.
The results do not provide support for a major role for skewed X-chromosome inactivation in female predisposition to autoimmunity; however, neither is the underlying hypothesis disproved by the present data.
As reviewed in Liu et al ., [ 15 ] several lines of evidence indicate that amino acids 9-23 of the insulin B chain also represent a major target of anti-islet autoimmunity in T1DM.