Example sentences for: autoimmunity

How can you use “autoimmunity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Second, if this actually leads to autoimmunity, it also predicts that the initial break in tolerance that leads to disease should involve an X-linked autoantigen that is expressed in a peripheral nontolerizing site or circumstance.

  • This tendency towards autoimmunity in females is often ascribed to hormonal differences because, in a number of experimental disease models, estrogens exacerbate disease and androgens can inhibit disease activity [ 3, 4].

  • In induced models of autoimmunity, the CD28-B7 interaction has been shown to regulate disease susceptibility by rendering autoreactive T cells anergic, or alternatively by upregulating the threshold for autoreactive T-cell activation [ 30 ] . Furthermore, we previously showed that impaired Fas-mediated activation-induced cell death (AICD) of autoreactive T-helper-1 cells may be responsible for the development of PGIA [ 20 ] . Therefore, AICD and/or T-cell anergy, but not the CD4 +CD25 +regulatory T cells, may be responsible for deletion or inactivation of autoreactive T cells in autoimmune arthritis.

  • It is noteworthy that immune serum from mice with ovarian autoimmunity reacts specifically with an oocyte-specific protein called MATER [ 24 25 ] . We have subsequently identified the homologous human MATER gene and protein [ 26 ] In ongoing work we are evaluating the value of MATER antibodies as a marker for autoimmune ovarian failure in women.

  • In this context, it has been shown [ 16] that transcription of the AR gene correlates inversely with repeat length.We therefore compared AR repeat length in control individuals and patients with autoimmunity.


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