Example sentences for: autoimmunity

How can you use “autoimmunity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This tendency towards autoimmunity in females is often ascribed to hormonal differences because, in a number of experimental disease models, estrogens exacerbate disease and androgens can inhibit disease activity [ 3, 4].

  • Although it has been shown that the CD4 +CD25 +regulatory T cells can suppress the development of autoimmunity, a recent report [ 27 ] demonstrated that depletion of the CD4 +CD25 +T cells is necessary but not sufficient for induction of autoimmune gastritis.

  • Recent studies have mentioned HCV incidence in patients with 1SS ranging from 14-19% [ 11 12 16 18 21 ] . Phenotypic characterization of the minor salivary glands with immunohistochemistry in patients with hepatitis C virus infection and/or 1°SS has given conflicting results [ 14 15 ] Some reports mention that the salivary gland findings are strikingly similar in patients with liver disease associated with HCV infection than in those with 1°SS [ 12 ] , while others mention distinctive differences between both groups regarding focus score, expression of surface markers in lymphocytes infiltrating the salivary glands and in epithelial cells, as well as differences in the degree of inflammation [ 14 15 ] . Transgenic mice models that carry the HCV envelope genes develop an exocrinopathy affecting salivary and lachrymal glands [ 19 ] . Expression of autoimmunity markers also tends to differ between HCV-infection and 1°SS.

  • In humans, antigen-specific anaphylactic reactivity is thought to be mediated solely (or primarily) by IgE antibodies, whereas it has long been known that either IgE or IgG1 antibodies can mediate anaphylaxis in mice (reviewed in [ 14 15 ] and [ 17 ] ). However, it has been reported that IgG1-dependent anaphylaxis in the mouse is associated with substantially less histological evidence of mast cell degranulation than is observed in IgE-dependent anaphylaxis in that species [ 17 ] . In neither of the models of "autoimmunity" that we have studied (i.e.

  • In addition, many childhood forms of autoimmunity, such as juvenile rheumatoid arthritis, exhibit female predominance [ 5].


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