Words similar to autoinhibitory

Example sentences for: autoinhibitory

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The protein kinase domain in CRKs shows strong sequence similarity to the kinase domain in CPKs, but the autoinhibitory and CLDs in CRKs show weak sequence similarity to the corresponding domains in CPKs.
In the inactive state, the Rho-binding domain and the pleckstrin homology domain form an autoinhibitory loop by binding and blocking the kinase domain at the N-terminus of the molecule.
Ppt1p shares several biochemical properties with PP5 and other homologs, including a similar domain structure and stimulation by lipid in vitro . Unlike PP5, Ppt1p is not fully activated by removal of the TPR domain or by removal of 9 C-terminal residues, suggesting that these regions may not play an autoinhibitory role in Ppt1p.
CPKs range from 453 to 646 amino acids (Table 2) with four distinct domains; a variable region at the amino terminus (approximately 22-184 amino acids), a serine/threonine protein kinase domain (approximately 275 amino acids), an autoinhibitory domain (also called the junction region) (approximately 31 amino acids) and the regulatory CLD (approximately 165 amino acids) (Figure 2).
CPKs have basal activities in the absence of Ca 2+as a result of the presence of the autoinhibitory region.