Words similar to arr
Example sentences for: arr
How can you use “arr” in a sentence? Here are some example sentences to help you improve your vocabulary:
Figure 1), but both wild-type and mutant LRP6, unlike the LRP homolog Arr, activated signaling about 10- to 15-fold alone, 2- to 4-fold when co-transfected with Wg, and 4- to10-fold when co-transfected with DFz2.
Therefore it is most likely that Wg, DFz2 and LRP/Arr form a trimeric ligand-receptor complex to activate the signaling pathway.
To explore these issues, we used dsRNAi to reduce the levels of Arr and DFz2 RNAs in S2 cells in which Wg signaling was stimulated, since others have shown that the expression of endogenous genes in these cells can be eliminated or reduced by direct application of T7-transcribed dsRNAs [ 15 16 ] . Using this approach (Figure 2), we found that the previously observed, approximately 30-fold stimulation of luciferase activity by the Wg expression plasmid was reduced by 70% or more when S2 cells were co-transfected with inhibitory RNAs for Arr, DFz2, or both (Figure 2A), implying that endogenous levels of both types of receptor are required for an efficient response to Wg.
Two of these classes are bacterial (one typified by the arsC found in enteric bacteria such as E. coli ; the other typified by the arsC found in Staphylococcus plasmids and other Gram-positive Bacteria); the third is the Arr2 gene of S. cerevisiae . Phylogenies of these gene families based on 18 arsC sequences were recently reported [ 30 ] . However, as well as microorganisms that have been shown to have demonstrable arsenate resistance, whole genome analyses of various microorganisms have revealed an increasing number of open reading frames (ORFs) that have homology to arsC . Inclusion of these putative arsC genes in phylogenetic analyses might resolve the basic question: Did arsenate resistance systems evolve from a common origin or develop convergently in multiple taxa?
Alternatively, however, it is possible that Wnt/Wg can signal through LRP/Arr in the absence of Fzs.
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