Words similar to arpe-

Example sentences for: arpe-

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This agent at concentrations higher than 10 μM was toxic to ARPE-19 cells by itself and could enhance H 2 O 2 toxicity (results not shown).
Since ERK activation appeared to be an early event associated with H 2 O 2 induced cytotoxicity, experiments were performed to determine if inhibitors of ERK activation could affect the cytotoxicity caused by H 2 O 2 . ARPE-19 cells were pretreated with 10 μM PD98059 (a MEK inhibitor which functions upstream of ERK [ 33 ] ) followed by H 2 O 2 challenge.
H 2 O 2 induced cytotoxicity in RPE cells appears to be affected by the density of cells in cultures [ 29 ] . To study this phenomenon, ARPE-19 cells plated in 96-well plates with densities of 10,000, 20,000 or 40,000 cells/well were subjected to H 2 O 2 treatment.
Both AG126 (10 μM) and 15d-PGJ 2 (1 μM) could prevent H 2 O 2 induced cytotoxicity in ARPE-19, a set of experiments was also performed to determine whether these two agents had additive saving effects.
Results from this study indicated that both primary human RPE cultures and ARPE-19 cells were susceptible to H 2 O 2 treatment.