Example sentences for: antagonists

How can you use “antagonists” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Hibert et al proposed an early model for the antagonist pharmacophore of the 5-HT 3 R [ 18 ] . According to this model, all 5-HT 3 R antagonists contain an aromatic ring, a carbonyl oxygen or bioisosteric equivalent, and a basic nitrogen.

  • Their molecular properties were at first surprising: they proved to be antagonists of other signaling factors, mostly of bone morphogenetic proteins (BMPs) and also of WNT (a secreted protein homologous to the

  • In the sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI), peripheral alpha-1 antagonists are recommended not only as second-line anti-hypertensive therapy after low-dose diuretics and beta blockers, but also for specific indications such as therapy in men with hypertension and prostatism [ 2 ] . Alpha-1 antagonists represent effective therapy for prostatism, and fifty percent of men have histologic evidence of BPH by 60 years of age [ 3 4 ] . The National Ambulatory Medical Care Survey reported that the number of people on any type of peripheral alpha-1 antagonist in 1995 was approximately 6 to 7% of those with hypertension [ 5 ] . About 80% of surveyed physicians would choose these drugs as a first-line blood pressure agent for patients with hypertension and symptoms of BPH [ 6 ] .

  • Medline and the Cochrane databases were used to identify English-language papers on peripheral alpha-1 antagonists in studies targeting cardiovascular endpoints, background physiologic literature, or any studies suggesting mechanisms leading to an inferior performance in cardiovascular endpoints.

  • Serotonin antagonists have been very effective in treating chemotherapy-associated nausea (eg, ondansetron) [ 58 ] . They have been reported to be useful for refractory nausea of diverse types but are typically tried only when other medications have failed.

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