Words similar to antagonism
Example sentences for: antagonism
How can you use “antagonism” in a sentence? Here are some example sentences to help you improve your vocabulary:
Spinal antagonism of either alpha1 or alpha2 adrenergic receptors was reported to increase micturition volume [ 17 ] in anesthetized rats.
It is processed to GC's through the actions of 21 hydroxylase and 11 β-hydroxylase [ 44 ] and it is an anti-GC [ 45 46 47 48 49 ] and an anti-mineralocorticoid (MC) [ 50 51 52 53 ] . Therefore, PR antagonism by RU486 could increase GC and MC effects, although this is the opposite of the phenotype seen.
In cats, serotonin antagonists caused a decrease in bladder capacity [ 43 ] however in anesthetized rats, serotonin antagonism did not have an effect on micturition [ 44 ] . Recently, a selective 5-HT1A receptor antagonist (WAY-100635) was reported to inhibit bladder contractions in rats [ 45 ] yet another report only observed an increase in the pressure threshold [ 46 ] . Olanzapine and risperidone have only low to modest affinity for the 5-HT1A receptor, and higher affinities for the 5-HT2A and 5-HT2C receptors [ 11 12 ] . Serotonin 5-HT2 and 5-HT3 receptors facilitate pudendal reflexes in the cat [ 47 48 ] , therefore it is possible that antagonism of these receptors may block the EUS in the anesthetized rat.
Whereas, protection by RU486 implies antagonism of GR mediated bone loss, rather than antagonism of PR mediated bone remodeling.
For example some investigators have suggested that opioid ligands with agonism at μ opioid receptors and antagonism at δ opioid receptors are potentially useful analgesics [ 5 6 7 ] . In cases where the medicinal effect of a drug is mediated through the same opioid receptor type that also elicits the side effects, the use of drugs with mixed activity could be most beneficial [ 7 ] . In such a case, interaction with one receptor could reverse the unwanted side effects associated with activation of the other receptor.
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