Words similar to antagonism
Example sentences for: antagonism
How can you use “antagonism” in a sentence? Here are some example sentences to help you improve your vocabulary:
Certainly I see…antagonism of some of these pathways that nicotine activates or the complementary activation of the cannabinoid pathways as very important targets for therapeutics with respect to the anorexia that's associated with chemotherapy.”
Selective antagonism of D2 receptors only modestly reduced the amplitude of HFO without affecting any other urodynamic parameters [ 6 35 ] . Therefore, it is possible that olanzapine and risperidone decrease the amplitude of the HFO, at least partly, through antagonism of D2 receptors.
In cats, serotonin antagonists caused a decrease in bladder capacity [ 43 ] however in anesthetized rats, serotonin antagonism did not have an effect on micturition [ 44 ] . Recently, a selective 5-HT1A receptor antagonist (WAY-100635) was reported to inhibit bladder contractions in rats [ 45 ] yet another report only observed an increase in the pressure threshold [ 46 ] . Olanzapine and risperidone have only low to modest affinity for the 5-HT1A receptor, and higher affinities for the 5-HT2A and 5-HT2C receptors [ 11 12 ] . Serotonin 5-HT2 and 5-HT3 receptors facilitate pudendal reflexes in the cat [ 47 48 ] , therefore it is possible that antagonism of these receptors may block the EUS in the anesthetized rat.
Earlier, we presented evidence that a regulator of G protein signaling, RGS3, might participate in the regulation of GnRH receptor signaling [ 9 ] . The mechanism of RGS action is antagonism of the Gα protein either by accelerating its hydrolysis of GTP, thereby prematurely terminating signaling due to reassociation of the Gα and Gβγ complexes [ 10 ] , or by antagonizing interaction of the Gα protein with its effector such as phospholipase Cβ [ 11 12 ] . A large number of RGS genes have been identified in mammals based on the presence of a 120 amino acid core domain [ 13 14 15 16 ] . RGS proteins have been described that interact with the G i α and G qα members of the G protein family [ 17 18 19 20 21 ] .
In murine pre-adipocytes, it is transcriptionally up regulated by long chain free FAs via a PPARα-mediated process [ 66 ] . Approaches using antisense technology, null mice, transgenic mice, and microarrays revealed important additional roles of CD36 protein as a receptor for thrombospondin, collagen type I, and oxidized LDL on macrophages [ 67 ] . The up regulation of Cd36 with FISH, and antagonism in presence of FUNG, merits further study.
Loading...