Words similar to antagonism
Example sentences for: antagonism
How can you use “antagonism” in a sentence? Here are some example sentences to help you improve your vocabulary:
A third mechanism by which chloroquine and chemically related drugs such as mefloquine might interfere with thyroid function is through structural homology to T 3 , resulting in thyroid hormone antagonism.
In a letter last March 28, she said her decision was based on years of unresolved problems with Passaic, combined with its "hostility and antagonism."
A CI value < 1 indicates synergy and that of > 1 indicates antagonism.
However, intrathecal atipamezole (alpha2 antagonist) increased residual volume in awake rats [ 18 ] . Therefore, it is difficult to interpret clozapine's effects on micturition volume in terms of spinal alpha adrenoceptor antagonism and possibly the supraspinal effects predominate.
Our data clearly show that nalbuphine is a potent agonist at the μ opioid receptor with an efficacy similar to that of morphine, thus agreeing with in vivo data showing that morphine and nalbuphine are equally potent as analgesics [ 33 ] . However, other reports have described nalbuphine as a "mixed agonist/antagonist" with agonism at κ opioid receptors and antagonism at μ opioid receptors based on in vivo data [ 11 33 ] . This categorization is likely due to the fact that nalbuphine has been shown to reduce the ventilatory depressant effect of other opioids, while adding to their analgesic effect [ 33 ] . Nalbuphine is also used clinically to reduce the opioid-mediated side effects such as itching, without completely reversing the analgesic effects of the full agonists [ 34 35 36 ] . According to our data, although nalbuphine is clearly a potent agonist at μ receptors, its levels of agonism is significantly lower than the very efficacious drug fentanyl and the endogenous ligand β-endorphin.
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