Example sentences for: antagonist

How can you use “antagonist” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The GABAa antagonist bicuculline also widened vertebral arch distance at the 0.5 and 1 mg/kg doses (p < .05), but not at the 2 mg/kg dose.

  • These would be drugs that act as an agonist at one receptor and as an antagonist or partial agonist at another receptor type.

  • Hibert et al proposed an early model for the antagonist pharmacophore of the 5-HT 3 R [ 18 ] . According to this model, all 5-HT 3 R antagonists contain an aromatic ring, a carbonyl oxygen or bioisosteric equivalent, and a basic nitrogen.

  • While both these ligands bind with high affinities (less than 1 nM) to μ opioid receptors, WIN 44,441 acts as an antagonist at μ opioid receptors and xorphanol is a very weak agonist at μ opioid receptor (Gharagozlou et al.

  • These results strongly support the model, initially hypothesized for cyclopamine [ 11 ] , that the reduced potency observed for Hh antagonists on Smo act-expressing cells is directly due to a reduced affinity of the antagonist for the mutated Smo protein.


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