Words similar to anaphylatoxin
Example sentences for: anaphylatoxin
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The above strategy was used to perform colony blot hybridization screening on the monkey cv-1 cDNA library using a ~750 bp P 33-labeled probe to a region of the fibulin-1C gene containing most of the type I anaphylatoxin repeats and almost all of the type II EGF-like repeats (Fig.
3), containing half of the anaphylatoxin type I repeats, an EGF-adjoining sequence, calcium-binding EGF-like modules and a carboxyl-terminal fibulin-type module, demonstrated interaction with the extracellular domain of proHB-EGF (Additional file 1).
Fibulin-1 is a calcium-binding extracellular matrix glycoprotein that is associated with various connective tissues, basement membranes and blood [ 37 38 39 ] . Splicing of the C terminal domain of fibulin-1 can lead to the expression of different variants of fibulin-1 (A-D) [ 37 ] . The amino acid sequence of the human fibulin-1C protein encodes five domains: a signal sequence (35 amino acid residues), three anaphylatoxin type I repeats (108 residues), an adjoining sequence (33 amino acid residues), nine calcium-binding type II EGF-like modules (387 amino acid residues), and a carboxyl domain (116 amino acid residues) [ 37 ] . The amino acid sequence derived from the nucleotide sequence obtained for monkey fibulin-1C (GenBank accession number AF395659) shows it to share 97.