Example sentences for: ais

How can you use “ais” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To identify the effects of androgen treatment on gene expression in genital fibroblasts, we carried out a set of 21 DNA microarray analyses of mRNA from normal and AIS genital fibroblasts.

  • We could not identify mutations in the AR gene in two phenotypically female individuals with complete AIS.

  • A critical question raised by these results is whether the observed differences between genital fibroblasts from males and AIS females reflect cell-autonomous effects of androgen exposure during development, or indirect effects of the AR-dependent genital morphogenetic program.

  • We tested the responses of normal and AIS genital fibroblasts to dihydrotestosterone (DHT), under culture conditions similar to those that were reported to produce aromatase induction in these cells [ 8 ] . Cells were treated with DHT (100-1,000 nM) both at confluency (G 0 ) and during exponential growth, and transcript levels were assessed using DNA microarrays.

  • No differences in transcript levels could be discerned between DHT treated and control cells in either normal foreskin fibroblasts or fibroblasts from AIS affected 46, XY females.


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