Words similar to ais-derived
Example sentences for: ais-derived
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Many of these differences between normal and AIS-derived fibroblasts were also observed in gonadal fibroblasts, suggesting that these differences are not purely due to differences in the anatomical site of origin of the fibroblasts.
Hierarchical cluster analysis of these experiments clearly showed the distinct differences in transcriptional profiles between AIS-derived and normal male fibroblasts and between proliferating and normal fibroblasts (Figure 3).
On the right, the regions of the cluster diagram are indicated which differentiate between normal and AIS-derived fibroblasts, and proliferating and confluent cells, respectively.
et al . found significantly different baseline expression levels of insulin-like growth factor (IGF) and insulin-like growth factor binding protein (IGFBP) between normal and AIS-derived genital skin fibroblasts, and could not detect changes in transcript levels in response to androgen treatment [ 29 ] . In normal genital fibroblasts, androgen-responsive reporter genes can only be activated by expression of co-transfected AR in the presence of ligand [ 30 ] . Therefore, endogenous AR expression itself may be insufficient in genital skin fibroblasts to elicit a transcriptional response.