Example sentences for: ais-derived

How can you use “ais-derived” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The second fibroblast line from an AR mosaic patient, ARD465 (Table 1), had very low wild-type AR expression and showed baseline gene-expression patterns that were nevertheless more similar to normal male foreskin and prostate fibroblasts than to any of the AIS-derived cell lines (Figure 2).

  • On the right, the regions of the cluster diagram are indicated which differentiate between normal and AIS-derived fibroblasts, and proliferating and confluent cells, respectively.

  • For example, cadherin 13 ( CDH13 ), versican ( CSPG2 ), collagen 8A1 ( COL8A1 ), collagen 12A1 ( COL12A1 ), P4HA2 (encoding a procollagen-modifying enzyme) all showed relatively low expression in the genital skin fibroblasts of normal males, whereas tenascin XB ( TNXB ), nidogen 2 ( NID2 ), laminins ( LAMA3 , LAMA4 ) and tissue inhibitor of metalloproteinase 1 ( TIMP1 ) all showed relatively high expression levels compared to AIS-derived fibroblasts (Figure 2).

  • et al . found significantly different baseline expression levels of insulin-like growth factor (IGF) and insulin-like growth factor binding protein (IGFBP) between normal and AIS-derived genital skin fibroblasts, and could not detect changes in transcript levels in response to androgen treatment [ 29 ] . In normal genital fibroblasts, androgen-responsive reporter genes can only be activated by expression of co-transfected AR in the presence of ligand [ 30 ] . Therefore, endogenous AR expression itself may be insufficient in genital skin fibroblasts to elicit a transcriptional response.

  • Many of these differences between normal and AIS-derived fibroblasts were also observed in gonadal fibroblasts, suggesting that these differences are not purely due to differences in the anatomical site of origin of the fibroblasts.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast