Words similar to ais-derived

Example sentences for: ais-derived

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However, we were unable to detect any significant changes in gene-expression patterns in cultured, AR-expressing genital fibroblasts or in AIS-derived fibroblasts in response to androgens.
On the right, the regions of the cluster diagram are indicated which differentiate between normal and AIS-derived fibroblasts, and proliferating and confluent cells, respectively.
Hierarchical cluster analysis of these experiments clearly showed the distinct differences in transcriptional profiles between AIS-derived and normal male fibroblasts and between proliferating and normal fibroblasts (Figure 3).
et al . found significantly different baseline expression levels of insulin-like growth factor (IGF) and insulin-like growth factor binding protein (IGFBP) between normal and AIS-derived genital skin fibroblasts, and could not detect changes in transcript levels in response to androgen treatment [ 29 ] . In normal genital fibroblasts, androgen-responsive reporter genes can only be activated by expression of co-transfected AR in the presence of ligand [ 30 ] . Therefore, endogenous AR expression itself may be insufficient in genital skin fibroblasts to elicit a transcriptional response.
The second fibroblast line from an AR mosaic patient, ARD465 (Table 1), had very low wild-type AR expression and showed baseline gene-expression patterns that were nevertheless more similar to normal male foreskin and prostate fibroblasts than to any of the AIS-derived cell lines (Figure 2).