Words similar to ais-affected
Example sentences for: ais-affected
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These female AIS-affected individuals are thought to have acquired their AR gene mutations post-zygotically [ 12 ] . ARD364, which showed AR protein expression and binding in the range of normal male foreskin fibroblasts ( [ 7 ] and see Table 1), despite its origin from anatomically female genitalia, had a gene-expression pattern indistinguishable from foreskin fibroblasts of normal males (Figure 2).
Comparison of expression patterns in genital fibroblasts from normal and AIS-affected individuals, and fibroblasts from extragenital sites, offers possible insights into the programs that underlie genital development.
In contrast, SAM analysis identified 1,664 transcripts that differed significantly between proliferating and confluent cells, and 1,232 transcripts that differed between fibroblasts derived from AIS-affected individuals and normal male foreskin.
The analysis was based on 2,862 transcripts that differed significantly between proliferating and confluent cells and between fibroblasts derived from AIS-affected individuals and normal male foreskin, respectively, as identified by SAM analysis of the treatment series.
Comparison of gene-expression patterns in genital fibroblasts from normal and AIS-affected individuals, and in fibroblasts from extragenital sites, may offer clues to the programs that underlie external genital development.