Example sentences for: aggregate

How can you use “aggregate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Indeed, a similar explanation has been invoked to explain the presence of Hsp70 and ubiquitin in nuclear aggregates observed in cells expressing abnormal gene products with poly-Gln tracts, such as huntingtin [ 54 ] and ataxin-1 [ 59 ] . Based on reports that overexpression of chaperones [ 59 62 ] or a dominant-negative form of the ubiquitin-conjugating enzyme [ 63 ] can suppress the formation of poly-Gln protein aggregates, Kaytor and Warren [ 58 ] proposed a three-stage model wherein (i) molecular chaperones initially associate with the misfolded protein, (ii) failure to diminish the pool of misfolded protein leads to aggregation and ubiquitination and (iii) inefficient degradation of the aggregate by the proteasome is manifested by the accumulation of inclusion bodies.

  • Inpatient pharmacy costs are included in the aggregate hospital charges, and cannot be separated out.

  • Although aggregate household wealth has risen in part as a result of the stock market boom over the 1990s, many individual households have accumulated little, if any, wealth.

  • In compliance with the Internal Revenue Service Restructuring and Reform Act of 1998, IRS's bonus totals cannot exceed 5 percent of the aggregate career senior executive basic pay.

  • Strict conformation requirements for aggregate formation can also explain interspecies transmission barriers, where prion domains of Sup35 derived from other yeast species cannot cause formation of [PSI + ] prion in Saccharomyces cerevisiae, in spite of a high degree of homology.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast