Example sentences for: aggregation

How can you use “aggregation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For more complex traits, the inheritance pattern does not fit a single-gene model, and methods that assume a genetic model may provide erroneous results [ 59 ] . Ischemic stroke clearly demonstrates familial aggregation, yet no single-gene model of transmission is consistent with the family data.

  • Cyclooxygenase inhibition by aspirin has little effect on initial aggregation in response to shear forces.

  • Even if a protein with a polyQ domain does not form a prion, its aggregation may depend on certain prions.

  • These changes include astrogliosis, fragmentation of Golgi apparatus, SOD1 aggregation and vacuolar degeneration [ 7 11 12 13 14 ] . Vacuolar degeneration is most prominent at the onset of the disease and precedes motoneuron death by two to three months [ 15 ] . Although the high expresser line of SOD1 G93Ashowed vacuoles derived from both endoplasmic reticulum and mitochondria [ 13 ] , the lower expresser line of SOD1 G93A, which more closely mimics the human SOD1 levels [ 16 ] , showed vacuoles that are nearly all developed from degenerating mitochondria [ 15 17 ] . Mitochondrial vacuolation was also reported in another transgenic line SOD1 G37R [ 7 ] .

  • Molecular chaperones bind to nascent proteins in the endoplasmic reticulum (ER), promote proper protein folding, and prevent the aggregation of nonnative and misfolded proteins.


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