Example sentences for: aggregation

How can you use “aggregation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The prion domains are the major structural determinants that are solely responsible for the polypeptide aggregation and propagation of the aggregates.

  • The CD98 (4F2, FRP-1) molecule, a cell surface disulfide-linked heterodimer, was originally described as a T cell activation antigen [ 1 ] , and later was shown to provide a co-stimulatory signal for CD3-mediated T-cell activation [ 2 ] , independent of CD28/CD80/CD86 interaction [ 3 ] . In other studies, triggering of human monocyte CD98 could suppress T cell proliferation [ 4 ] , or promote homotypic cell aggregation of monocytes [ 5 ] . Also, CD98 may be a target antigen for natural killer cells [ 6 ] , may mediate fusion of blood monocytes leading to osteoclast formation [ 7 8 ] , and may modulate hematopoietic cell survival and differentiation [ 9 ] .

  • Therefore, pending further investigation, we cannot rule out the alternative hypothesis that mutations in the N(T)KxD motif of Rab24, combined with features in the C-terminal domain, cause Rab24 to misfold in a unique manner, attracting non-physiological protein partners that can promote aggregation and nuclear localization.

  • 2, 10) suggests that mutant SOD1 interacts with mitochondrial membrane and this interaction promotes aggregation.

  • The early aggregation phenotype associated with BS153 suggests that the cAMP pulsing system was established earlier than normal.


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