Words similar to adrenalectomy

Example sentences for: adrenalectomy

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In any case, none of these considerations compromise the basic observation that adrenalectomy failed to reverse diet-induced obesity.
The further elevation in POMC expression observed after adrenalectomy of the obese mice could plausibly be due to elevated leptin combined with decreased glucocorticoids, since glucocorticoids may antagonize the effects leptin [ 30 ] .
Furthermore, the effect of adrenalectomy on hypothalamic POMC mRNA may also depend genetic background [ 6 26 27 ] . Nevertheless, we hypothesized that if adrenalectomy enhanced hypothalamic POMC mRNA in diet-induced obesity in mice, as in leptin-deficient mice, adrenalectomy would also reverse obese phenotypes in mice that became obese due to a high-fat diet.
As observed in leptin-deficient ob/ob mice, adrenalectomy in diet-induced obese mice led to a striking increase in hypothalamic POMC mRNA (Fig.
In the present study, adrenalectomy and corticosterone implants were used to address the role of elevated corticosterone in mediating the effects of fasting and insulin deficiency on hypothalamic gene expression, resulting in several novel observations.