Example sentences for: adrenalectomy

How can you use “adrenalectomy” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Streptozotocin injection led to reduced body weight and adiposity in sham-operated animals as previously described [ 5 17 ] (Table 2), whereas adrenalectomy attenuated the loss of both body weight and adiposity associated with insulin deficiency (Table 2).

  • Adrenalectomy produced a non-significant trend toward an increase in hypothalamic POMC mRNA in sham-operated mice, but a 5-fold induction of POMC mRNA in mice on the high-fat diet (Fig.

  • Although the mechanisms through which adrenalectomy acts to reverse obesity is not entirely clear, it is plausible that the mechanisms entail enhanced hypothalamic POMC production [ 6 ] . Hypothalamic POMC mRNA is reduced in several forms of obesity [ 18 19 20 ] . Conversely, reversal of obese phenotypes by adrenalectomy is associated with a restoration of hypothalamic POMC mRNA tone in leptin-deficient ob/ob mice [ 6 ] . Furthermore, the melanocortin agonist MTII (which mimics the key anti-obesity product of POMC, alpha-MSH) reduces body weight in diet-induced obesity [ 21 ] . On the other hand, the effect of diet-induced obesity on hypothalamic POMC mRNA is somewhat complex and may depend on the genetic background [ 22 23 ] , and duration of the diet [ 24 25 ] or composition [ 23 ] of the diet.

  • Effects diet and adrenalectomy on body weight, adipose weight and caloric intake

  • As with AGRP, NPY mRNA was also elevated after fasting, and this effect of fasting on NPY mRNA was also completely blocked by adrenalectomy (Fig 2C).


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