Example sentences for: adriamycin

How can you use “adriamycin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The present study was directed to the reversal activity of NOM on MDR in adriamycin (ADR)-resistant (MCF7/ADR) cells, and to compare NOM with classic reversal agents [verapamil (VRP), tamoxifen (TAM), droloxifene (DRO) and MG].

  • Cells treated with HGF/SF and Adriamycin also had modified cell line regulation and signal transduction that might suggest mechanisms by which HGF/SF exerts its protective activity [ 31 ] .

  • The significance of HGF/SF as a marker of poor prognosis might also be associated with its effects on acquired resistance to anti-cancer drugs [ 35 36 ] . HGF/SF protects cancer cells from DNA-damaging chemotherapy agents through pathways involving signaling from Met to phosphoinositide 3-kinase and c-Akt [ 29 ] . Human breast cancer cells, preincubated with HGF/SF and then exposed to Adriamycin, exhibit an altered pattern of gene expression compared with cells treated with Adriamycin alone.

  • ADR = adriamycin; DRO = droloxifen; GSTπ = glutathione S-transferase Pi; MDR = multidrug resistance; MG = megestrol; MRP = MDR-related protein; MTT = 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2 H -tetrazolium bromide; NOM = nomegestrol; PBS = phosphate-buffered saline; P-gp = P-glycoprotein; RT-PCR = reverse transcriptase polymerase chain reaction; TAM = tamoxifen; TopoIIα = topoisomerase IIα; VRP = verapamil.


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