Example sentences for: adr

How can you use “adr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • ADR = adriamycin; DRO = droloxifen; GSTπ = glutathione S-transferase Pi; MDR = multidrug resistance; MG = megestrol; MRP = MDR-related protein; MTT = 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2 H -tetrazolium bromide; NOM = nomegestrol; PBS = phosphate-buffered saline; P-gp = P-glycoprotein; RT-PCR = reverse transcriptase polymerase chain reaction; TAM = tamoxifen; TopoIIα = topoisomerase IIα; VRP = verapamil.

  • The development of MCF7/ADR cells was induced by treating MCF7/WT with ADR.

  • However, no change in TopoIIα gene expression level was detected in NOM-treated MCF7/ADR cells, indicating that the reversal effect of NOM on MDR in MCF7/ADR cells cannot result from modulating the gene expression of TopoIIα.

  • Accumulation of ADR was monitored using a standard procedure by incubating MCF7/ADR cells (5 × 10 5/ml) for 2 h at 37°C in the presence of ADR (10 μM) alone or in combination with NOM (20, 10 or 5 μM).

  • Before use in experiments, MCF7/ADR cells were cultured in drug-free medium for 2 weeks.


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