Example sentences for: adduct

How can you use “adduct” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This study demonstrates that oxidative stress induced by H 2 O 2 could lead to RPE cell death, which is preceded by distinct morphological changes, ERK activation and 4-HNE protein adduct formation.

  • 4 [2M+Na] +, the sodium adduct of the dimer.

  • For example, levels of 4-HNE increased significantly in the vitreous of patients with proliferative vitreoretinopathy compared with controls [ 17 ] . Further, 4-HNE forms a stable adduct with rhodopsin in the photoreceptor, which may interfere with its functions [ 18 ] . 4-HNE even causes cataracts in cultured rat lens [ 19 20 ] . Whether oxidative stress on RPE can cause accumulation of cellular HNE-protein adducts remains unknown.

  • The reason for this is that we found high levels of background staining with the anti-8-OH-dG antibodies, which is not unusual when using streptavidin/biotin detection systems in immunohistochemistry [ 39 ] . Unfortunately, secondary antibodies directly linked to a fluorophore or a detection enzyme were not sensitive enough to detect the 8-OH-dG adduct in our hands.

  • In the present studies, MDA was confirmed to be the predominant TBA-reacting adduct by high-performance liquid chromatography analysis of representative samples.


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